NAD (Nicotinamide Adenine Dinucleotide) is more than just a buzzword in the beauty and wellness industry; it’s a vital molecule found in every cell of our bodies that.  It plays a critical role in energy production and regulates cellular aging. As we age, NAD levels naturally decline (our NAD+ levels halve every 20 years), leading to signs of ageing and health issues. Supplementing with NAD or its precursors can rejuvenate cells from the inside, potentially slowing down the ageing process.

Confused about the difference between NAD and NAD+? Here’s our handy breakdown:

• NAD: Is a molecule found in all living cells, which is critical for cellular processes. It exists in two forms: NAD+ and NADH.
• NAD+: Is the oxidised form of NAD. It plays a vital role in metabolic processes, acting as an electron acceptor. When NAD+ accepts electrons (and a hydrogen ion), it becomes NADH. This conversion is crucial in the body’s energy production processes, particularly in the mitochondria during cellular respiration.
• NADH: This is the reduced form of NAD. When NAD+ gains electrons (and a hydrogen ion), it becomes NADH. NADH then carries these electrons to the electron transport chain, a series of reactions that generate ATP, the primary energy currency of the cell.

In summary, NAD is a general term referring to the molecule in either its oxidized (NAD+) or reduced (NADH) state, while NAD+ specifically refers to the oxidized form. The balance and conversion between NAD+ and NADH are crucial for various cellular processes, including energy production, DNA repair, and cellular signaling.

NAD isn’t just about keeping your cells young; it’s also integral to converting food into energy. It acts as a coenzyme in metabolic reactions, especially in the mitochondria, the powerhouse of the cell. This means better NAD levels can enhance your energy, improve mental clarity, and boost overall wellness.

One of the superpowers of NAD+ is its ability to assist in DNA repair. Exposure to environmental stressors like UV rays and pollution can damage our DNA. NAD+ steps in to help repair this damage, ensuring our cells function optimally. This not only has implications for anti-aging but also for reducing the risk of certain diseases.

Research has shown a fascinating link between NAD and longevity. Higher levels of NAD are associated with increased lifespan in yeast, worms, and mice. While more research is needed in humans, the potential of NAD for enhancing lifespan and healthspan is a thrilling area of exploration in the beauty and health industry. Which is why billionaire Bryan Johnson, who has thrown millions of dollars into testing how to increase longevity with his company, Blueprint, incorporates NAD into his daily regimen.

NAD’s role in skin and our overall health is particularly exciting. By promoting cellular health, NAD can improve skin texture and reduce signs of aging. Some studies suggest that topical NAD or its precursors could be the next big thing in skincare, offering a novel way to maintain youthful, glowing skin.

There are three main ways to incorporate NAD into your beauty and wellbeing routine:

Through Skincare Products: Innovations in skincare have led to the development of products containing NAD or its precursors, like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). These ingredients can penetrate the skin to boost NAD levels, promoting cell repair and rejuvenation. Look for serums, creams, and masks that highlight NAD, NR, or NMN in their ingredient list.

We love: Dr. Sam Bunting’s Flawless Moisturiser Intense, a rich cream designed to boost NAD+ levels and repair the skin’s barrier and NAD focused brands INVITY and Intuisse.

Dietary Supplements: You can also boost NAD levels internally through dietary supplements.  Look for NR and NMN supplements – these precursors are converted into NAD in the body, offering a non-invasive way to enhance cellular health and vitality. It’s essential to consult with a healthcare provider before starting any supplement regimen. We love INVITY’s range.

IV Drips and Injections: For a more direct approach, NAD IV drips and injections are offered at many wellness clinics. Both deliver NAD directly into the bloodstream, bypassing the digestive system for immediate absorption. This method is often used for its potential anti-aging benefits and to improve energy levels and cognitive function.

In the UK, Get A Drip offers NAD+ injections from £100 and drips from @250, NADClinic in Marylebone has a range of infusions from £180 and Effect Doctors from £350. We would highly recommend consulting a medical professional prior to undergoing any medical treatment.